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Identification of Hemoglobins and Hemoglobinopathies by Electrophoresis on Cellulose Acetate Plates Impregnated with Citrate Agar
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1974
Year
GlycobiologyLaboratory HematologyBioanalysisHematologyAnalytical ChemistryClinical ChemistryLaboratory MedicineChromatographyHealth SciencesBiochemistryHeme TransportHeme HomeostasisCellulose Acetate PlatesPhysiologyMicrobiologyHemoglobin AbnormalitiesCitrate AgarMedicineHemicellulose
Abstract We describe a method of electrophoresis of hemoglobin on cellulose acetate plates impregnated with citrate agar, which remain stable for many months and are used to confirm rapidly the presence of hemoglobins S and C and the hemoglobinopathies associated with them. The method also provides excellent separations of hemoglobins F and A and reliable identification of genetically determined hemoglobin abnormalities in the newborn.