Cardiac β1-Adrenoceptor Autoantibodies in Human Heart Disease: Rationale and Design of the <u>E</u> tiology, <u>Ti</u> tre- <u>C</u> ourse, and <u>S</u> urvival (ETiCS) Study

Abstract

ETiCS is so far the largest clinical diagnostic study projected to address cardiac autoimmunity. It attempts to unravel the pathophysiology of cardiac autoantibody formation and persistence/clearance. ETiCS will enhance current knowledge on autoimmunity in human heart disease and promote endeavours to develop novel therapies targeting cardiac aabs.