Concepedia

Adjuvant chemotherapy after esophagectomy: Is there a role in the treatment of the lymph node positive thoracic esophageal squamous cell carcinoma?

Xiao Lyu, Jing Huang, Yousheng Mao, Yutao Liu, Qinfu Feng, Kang Shao, Shugeng Gao, Yong Jiang, Jinwan Wang, Jie He

Journal of Surgical Oncology · 2014 · 53 citations · 22 references

DOIFull text

Open access

Abstract

Postoperative taxane-based adjuvant chemotherapy improved survival of patients with lymph node positive thoracic ESCC compared with surgery alone. Further randomized prospective studies to confirm these findings are warranted.

References

22

Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomised controlled trial

The Lancet · 2002 · 1.5K citations

, , +10

A Randomized Trial Comparing Postoperative Adjuvant Chemotherapy with Cisplatin and 5-Fluorouracil Versus Preoperative Chemotherapy for Localized Advanced Squamous Cell Carcinoma of the Thoracic Esophagus (JCOG9907)

Nobutoshi Ando, Hoichi Kato, Hiroyasu Igaki et al. · Annals of Surgical Oncology · 2011 · 1.4K citations

, , +5

Chemotherapy Followed by Surgery Compared with Surgery Alone for Localized Esophageal Cancer

David P. Kelsen, Robert J. Ginsberg, Thomas F. Pajak et al. · New England Journal of Medicine · 1998 · 1.3K citations

Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer

William Allum, Sally Stenning, J Bancewicz et al. · Journal of Clinical Oncology · 2009 · 982 citations · Full text

Surgery Plus Chemotherapy Compared With Surgery Alone for Localized Squamous Cell Carcinoma of the Thoracic Esophagus: A Japan Clinical Oncology Group Study—JCOG9204

Nobutoshi Ando, Toshifumi Iizuka, Hiroko Ide et al. · Journal of Clinical Oncology · 2003 · 718 citations