Folic acid-conjugated nanostructured materials designed for cancer cell targetingElectronic supplementary information (ESI) available: experimental details; selected plots and spectra. See http://www.rsc.org/suppdata/cc/b3/b307878g/

Abstract

Shell cross-linked nanoparticles (SCKs) constitute a unique class of materials with amphiphilic core-shell morphology; SCKs are characterised by their structural integrity and available functionality to attach receptor-recognising or receptor-specific ligands on the shell surface and, therefore, hold great potential in drug delivery applications; in an attempt to develop novel, cancer cell specific delivery vehicles, folate receptor targeted SCKs have been prepared.