Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: A study using rats and knockout mice

Cytoprotection by prostaglandins in rats

André Robert, James E. Nezamis, C. Roy D. Lancaster et al. · Gastroenterology · 1979 · 1.7K citations

Medicine, Cell Biology, Pathology +3

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

Nobuko Futaki, Satoru Takahashi, Motofumi Yokoyama et al. · Prostaglandins · 1994 · 833 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

Fumitaka Ushikubi, Eri Segi‐Nishida, Yukihiko Sugimoto et al. · Nature · 1998 · 687 citations

Life Sciences, Neuroscience, Pharmacology +12

Failure of Parturition in Mice Lacking the Prostaglandin F Receptor

Yukihiko Sugimoto, A. Yamasaki, Eri Segi‐Nishida et al. · Science · 1997 · 617 citations

Medicine, Endocrinology, Gynecology +17

Mild irritants prevent gastric necrosis through "adaptive cytoprotection" mediated by prostaglandins

A. Robert, James E. Nezamis, C. Roy D. Lancaster et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1983 · 485 citations

Medicine, Pharmacology, Clinical Pharmacology +12