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Remarkable electron-withdrawing effect of the Ph<sub>2</sub>P(O)-ethynyl group: Ph<sub>2</sub>P(O)-ethynyl-substituted aryl halides and copper acetylides for tailor-made Sonogashira couplings

12

Citations

25

References

2015

Year

Abstract

Ph<sub>2</sub>P(O)-ethynylphenyl bromide showed higher reactivity in Sonogashira couplings than phenylethynylphenyl bromide because of the electron-withdrawing nature of the Ph<sub>2</sub>P(O) group.

References

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