Concepedia

Publication | Open Access

Serine Protease Activation Essential for Endothelial–Mesenchymal Transition in Vascular Calcification

DOIFull Paper Access

95

Citations

46

References

2015

Year

Jiayi Yao, Pierre Guihard, Ana M. Blázquez‐Medela, Yina Guo, Jeremiah H. Moon, Medet Jumabay, Kristina I. Boström, Yucheng Yao
Circulation Research

Abstract

Our results suggest that Sox2-mediated activation of specific serine proteases is essential for initiating EndMTs, and thus, may provide new therapeutic targets for treating vascular calcification.

References

YearCitations

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