A retrospective comparison of surgical removal and subsequent CO₂laser ablation versus topical administration of mitomycin C as therapy for equine corneolimbal squamous cell carcinoma

Abstract

Horses receiving adjunctive topical MMC therapy were no more likely to experience tumor recurrence than were horses undergoing CO(2) laser ablation in the horses in this study. Initiation of two to three rounds of MMC following epithelialization of the surgical site results in fewer major complications and achieves comparable disease resolution relative to treatment in the immediate postoperative period.