A Preliminary Study of the Chromosomes in Spontaneous Abortions

Abstract

Out of 73 cultures from spontaneously aborted embryos or fetuses, sacs and some other conceptive specimens, 37 were successfully grown in culture. Chromosome analysis revealed that, among these, there were 4 specimens with chromosomal abnormalities. They were one case each of triploidy/(69, XXY) and D-trisomy (47, XY), a male showing a high incidence of cells with chromatid-type breaks, and a female characterized by a heterozygousity of the 17th pair. The remaining 33 cases were chromosomally normal.