PNEUMOCOCCAL MENINGITIS IN ADULTS

Abstract

Article1 July 1952PNEUMOCOCCAL MENINGITIS IN ADULTSJOSEPH S. FEIBUSH, M.D., E. J. MURPHY, M.D., F.A.C.P., A. LUBART, M.D.JOSEPH S. FEIBUSH, M.D.Search for more papers by this author, E. J. MURPHY, M.D., F.A.C.P.Search for more papers by this author, A. LUBART, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-1-65 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite numerous recent optimistic reports concerning the rate of cure in pneumococcal meningitis, a review of 22 adult cases observed at the Morrisania City Hospital from 1943 through June, 1951, resulted in a more pessimistic and guarded prognosis. Although the almost 100 per cent mortality of this disease in the presulfonamide era is well documented, it is of particular interest to note that the cases herein presented were all treated with combined penicillin and sulfonamides. Despite this, 15 patients died, leaving a gross mortality rate of approximately 70 per cent, which is in sharp contrast to a 73 per cent...Bibliography1. ApplebaumNelsonAlbin EJM: The treatment of pneumococcus meningitis with penicillin: a study of 125 consecutive cases with 73 per cent recovery, Am. J. M. Sc. 218: 260-264, 1949. MedlineGoogle Scholar2. DowlingSweetRobinsonZellersHirsch HFLJAWHL: The treatment of pneumococcic meningitis with massive doses of systemic penicillin, Am. J. M. Sc. 217: 149-155, 1949. CrossrefMedlineGoogle Scholar3. HodesSmithIckes HMH: Sixty cases of pneumonococcic meningitis treated with sulfonamides, J. A. M. A. 121: 1334-1337, 1943. CrossrefGoogle Scholar4. LepperDowling MHHF: Treatment of pneumococcic meningitis with penicillin compared with penicillin plus aureomycin, Arch. Int. Med. 88: 489-494 (Oct.) 1951. CrossrefGoogle Scholar5. LowreyQuilligan GHJJ: The treatment of pneumococcal meningitis without intrathecal penicillin, J. Pediat. 33: 336, 1948. CrossrefMedlineGoogle Scholar6. NemirIsrael RLJ: Pneumococcic meningitis in infants and children: combined therapy using penicillin and sulfonamide, J. A. M. A. 147: 213-218 (Sept. 25) 1951. CrossrefMedlineGoogle Scholar7. WaringWeinstein GL: The treatment of pneumococcal meningitis, Am. J. Med. 5: 402-418, 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication January 9, 1952.From the Second Medical Division, Morrisania City Hospital, New York, N. Y., Dr. E. Flood, Director. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCrystalline Pancreatic Desoxyribonuclease as an Adjunct to the Treatment of Pneumococcal MeningitisACTH and adrenal steroids in the treatment of pneumococcal meningitis in adultsPneumococcal Meningitis. Mastoidectomy Adjunctive to Antibiotic TreatmentPNEUMOCOCCAL MENINGITIS 1 July 1952Volume 37, Issue 1Page: 65-74KeywordsDeath ratesMeningitisMortalityPenicillinSulfonamide ePublished: 1 December 2008 Issue Published: 1 July 1952 PDF downloadLoading ...