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THE GENETICS OF DOPA DECARBOXYLASE IN <i>DROSOPHILA MELANOGASTER</i> I. ISOLATION AND CHARACTERIZATION OF DEFICIENCIES THAT DELETE THE DOPA-DECARBOXYLASE-DOSAGE-SENSITIVE REGION AND THE α-METHYL-DOPA-HYPERSENSITIVE LOCUS
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1976
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BiologyChromatinDrosophila MelanogasterCytogeneticsMedicineGeneticsNatural SciencesGenetic PredispositionGenetic MechanismChromosome BiologyMolecular GeneticsGene FunctionChromosomal RearrangementSecond ChromosomeGene ExpressionLeft ArmEpigeneticsNeurogenetics
A detailed cytogenetic investigation of 16 overlapping deficiencies in the 36C-40A region on the left arm of the second chromosome (2L) in Drosophila melanogaster is reported. These deficiencies permit a localization of both the dopa-decarboxylase-dosage-sensitive region and the alpha-methyl-dopa-hypersensitive locus, l(2) amd, to the same region, 37B10-37C7.