Medical Entomology and Zoology · 1980 · 424 citations · 0 references
Natural SciencesComputational EngineeringComputational Fluid DynamicsFluid DynamicsFluid MechanicsBoundary-layer TheoryFlow BehaviorFlow ModelingFlow StabilityPartial Differential EquationsTurbulent FlowFlow DynamicsReservoir Inflow Transients
Oritavancin displayed concentration-dependent killing of MSSA, MRSA, VRSA, VISA, VSE and VRE. Oritavancin was more rapidly bactericidal against all strains tested than were vancomycin, teicoplanin, linezolid or daptomycin at physiologically relevant concentrations. These data support the conclusion that oritavancin exerts concentration-dependent bactericidal activity on recent, drug-resistant isolates of S. aureus and enterococci.