A study of metabolites as intermediate effectors in angiogenesis

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Life Sciences, Cell Biology, Molecular Biology +17

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

Dorit Shweiki, Ahuva Itin, Dov Soffer et al. · Nature · 1992 · 4.6K citations

Life Sciences, Physiology, Tissue Differentiation +11

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg et al. · New England Journal of Medicine · 1994 · 3.8K citations · Full text

Medicine, Ophthalmology, Vision Science +15

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

Karl H. Plate, Georg Breier, Herbert A. Weich et al. · Nature · 1992 · 2.3K citations

Medicine, Cancer Biology, Oncology +16

Determination of cell number in monolayer cultures

Robert J. Gillies, Nicolás Didier, Michael L. Denton · Analytical Biochemistry · 1986 · 649 citations

Life Sciences, Cell Biology, Cell Division +7