The roles of<i>GSTM1</i>and<i>GSTT1</i>null genotypes and other predictors in anti-tuberculosis drug-induced liver injury

Abstract

GSTM1 and GSTT1 null genotypes do not seem to play important roles in ATD-induced liver injury in Brazilians. However, there was evidence that GSTM1 polymorphisms were possibly related to the intensity of toxicity. Active HBV and initial high ALT could predict ATD-induced liver injury.