In Vitro Characterization of Botulinum Toxin Types A, C and D Action on Human Tissues: Combined Electrophysiologic, Pharmacologic and Molecular Biologic Approaches

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

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SNAP receptors implicated in vesicle targeting and fusion

Thomas Söllner, Sidney W. Whiteheart, Michael Brunner et al. · Nature · 1993 · 3.2K citations

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A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

Thomas Söllner, Mark K. Bennett, Sidney W. Whiteheart et al. · Cell · 1993 · 1.9K citations

Life Sciences, Molecular Biology, Neuroscience +15

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

Giampietro Schiavo, Fabio Benfenati, Bernard Poulain et al. · Nature · 1992 · 1.8K citations

Life Sciences, Neurobiology, Neuroscience +16

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

Juan Blasi, Edwin R. Chapman, Egenhard Link et al. · Nature · 1993 · 1.2K citations

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