New Nomenclature for the Human Tissue Kallikrein Gene Family

Abstract

1.02-1.55 (mean 1.30; SD 0.18), compatible with heterozygosity. No individuals homozygous for the Cys282Tyr mutation were identified. To validate the method for detection of the homozygous mutant genotype, the assay was performed on a blood sample from a known homozygote. The NSS ratios for this individual, in two evaluations, were 9.1 and 7.4, within the predicted range.