JNCI Journal of the National Cancer Institute · 1976 · 36 citations · 0 references
Life SciencesGeneticsHematologyCytogeneticsHuman GeneticsMedical GeneticsAnemiaChromosomal AbnormalitiesClinical CytogeneticsHematologic DisordersMolecular CytogeneticsNumerical Chromosome AbnormalitiesChromosome 5Q LossCytogenetics In Hematologic DiseaseHematologic AbnormalitiesHematologic FailureKaryotypic AbnormalitiesKaryotypic Abnormality DetectionKaryotypic HeterogeneityNumerical Karyotype Abnormalities
A further instance of the 5q-chromosome associated with a distinct type of aregenerative anemia strengthened the hypothesis of specificity and consistency of this karyotypic abnormality in a new hematologic entity. The Giemsa banding technique revealed that the deletion of the long arms of chromosome number 5 was interstitial: del (5) (pter leads to q12 : : q31 leads to qter).