The synthesis of indole-3-aldehyde and its homologues

Abstract

ONE of the many major difficulties encountered in the synthesis of tryptophan is that connected with the preparation ofthe parent substance, indole-3-aldehyde. Despite the exceedingly poor yields which Ellinger The only one, indeed, worthy of mention is that of Majima and The method, whilst it gives a primary yield of aldehyde higher than that obtained by Ellinger, suffers from the drawback that it is not applicable