Cost effectiveness of nonoperative management versus laparoscopic appendectomy for acute uncomplicated appendicitis

Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial

C. Vons, Caroline Barry, Sophie Maître et al. · The Lancet · 2011 · 668 citations

Medicine, Pharmacotherapy, Surgery +7

Assessing cost-effectiveness in healthcare: history of the $50,000 per QALY threshold

Scott D. Grosse · Expert Review of Pharmacoeconomics & Outcomes Research · 2008 · 649 citations

Pharmacy, Nephrology, Pharmacoeconomics +17

What Does the Value of Modern Medicine Say About the $50,000 per Quality-Adjusted Life-Year Decision Rule?

R. Scott Braithwaite, David Meltzer, Joseph T. King et al. · Medical Care · 2008 · 585 citations

Pharmacy, Insurance, Pharmacoeconomics +17

Appendectomy versus Antibiotic Treatment in Acute Appendicitis. A Prospective Multicenter Randomized Controlled Trial

Johan Styrud, Staffan Eriksson, Ingemar Nilsson et al. · World Journal of Surgery · 2006 · 534 citations

Medicine, Internal Medicine, Surgery +9

Randomized clinical trial of antibiotic therapy <i>versus</i> appendicectomy as primary treatment of acute appendicitis in unselected patients

Jeanette Hansson, Ulla Körner, Amir Khorram‐Manesh et al. · British journal of surgery · 2009 · 499 citations · Full text

Medicine, Internal Medicine, Surgery +8