From the morphological to the transcriptomic characterization of a compromised three-dimensional<i>in vitro</i>model mimicking atopic dermatitis

Abstract

The inflammatory context contributes to the morphological, functional and transcriptomic changes observed in AD skin. As a result, this compromised RE model shares some characteristics with those found in AD skin and thus can be used as a relevant tool for screening formulations and drugs for the treatment of AD.