Concepedia

Publication | Open Access

Lopinavir/ritonavir population pharmacokinetics in neonates and infants

DOIFull Paper Access

31

Citations

9

References

2011

Year

Ghislaine Firtion, Suzanne T. Anderson, Déborah Hirt, Caroline Solas, Gilles Peytavin, Albert Faye, Isabelle Thuret, Marthe Le Prevost, Carole Giraud, Hermione Lyall,
British Journal of Clinical Pharmacology

Abstract

Size and PMA explained some CL/F and V/F variability in neonates/infants. Based upon trough concentration limitations, suggested LPV/r dosing regimens were 40 mg 12 h(-1), 80 mg 12 h(-1) and 120 mg 12 h(-1) in the 1-2 kg, 2-6 kg and 6-10 kg group, respectively.

References

YearCitations

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