Concepedia

Publication | Closed Access

Evaluation of Antipsychotic Dose Reduction in Late-Life Schizophrenia

DOI

86

Citations

33

References

2015

Year

Ariel Graff‐Guerrero, Tarek K. Rajji, Benoit H. Mulsant, Shinichiro Nakajima, Fernando Caravaggio, Takefumi Suzuki, Hiroyuki Uchida, Philip Gerretsen, Wanna Mar, Bruce G. Pollock,
JAMA Psychiatry

Abstract

Antipsychotic dose reduction is feasible in patients with stable LLS, decreasing adverse effects and improving illness severity measures. The results of the present study suggest a lower therapeutic window of D2/3R occupancy in patients with LLS (50%-60%) than previously reported in younger patients (65%-80%).

References

YearCitations

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