Nanoscale · 2015 · 106 citations · 21 references
PharmacyBioengineeringPharmaceuticsDrug DeliveryNanoparticle Drug DeliveryPolymer ChemistryDrug Delivery EngineeringDrug Delivery SystemsDrug EncapsulationGelsHydrogelsNanoparticle Delivery SystemsDrug Delivery GelsDrug Delivery HydrogelsDrug Delivery PolymersHydrogel CarriersHydrogel Drug ReleasePolymer NanocarriersPolymeric Delivery SystemsPolymeric Nanocarriers
Particle-based delivery systems have a demonstrated value for drug discovery and development. Here, we report a new type of particle-based delivery system that has controllable release and is self-monitoring. The particles were composed of poly(N-isopropylacrylamide) (pNIPAM) hydrogel with an inverse opal structure. The presence of macropores in the particles provides channels for active drug loading and release from the materials.
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Jianping Ge, Yadong Yin · Angewandte Chemie International Edition · 2011 · 1.2K citations
Natural Sciences, Materials Engineering, Materials Science +17
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