Concepedia

c-erb B2 overexpression decreases the benefit of adjuvant tamoxifen in early-stage breast cancer without axillary lymph node metastases.

Chiara Carlomagno, Francesco Perrone, Ciro Gallo, Michelino De Laurentiis, Rossella Lauria, Alessandro Morabito, Guido Pettinato, Luigi Panico, Antonio D’Antonio, A R Bianco,

Journal of Clinical Oncology · 1996 · 409 citations · 25 references

DOI

Abstract

In early-stage breast cancer patients, overexpression of c-erbB2 is a marker of lack of efficacy of adjuvant tamoxifen.

References

25

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.6K citations

Evaluation of survival data and two new rank order statistics arising in its consideration.

Nathan Mantel · PubMed · 1966 · 7.6K citations

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Studies of the HER-2/ <i>neu</i> Proto-Oncogene in Human Breast and Ovarian Cancer

Dennis J. Slamon, William Godolphin, Lovell A. Jones et al. · Science · 1989 · 6.8K citations

Histological Grading and Prognosis in Breast Cancer

H. J. G. Bloom, W Richardson · British Journal of Cancer · 1957 · 2.9K citations · Full text

, , +6

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer

Hyman B. Muss, Ann D. Thor, Donald A. Berry et al. · New England Journal of Medicine · 1994 · 968 citations · Full text