Concepedia

Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma

Rolf E. Swenson, Miriam Harel, Sampa Jana, Erik Stolarzewicz, Timothy Hla, Linda H. Shapiro, Fernando Ferrer

Journal of Pharmacology and Experimental Therapeutics · 2015 · 26 citations · 25 references

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25

CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

Kenneth E. Lipson, Carol Wong, Yuchin Teng et al. · Fibrogenesis & Tissue Repair · 2012 · 578 citations · Full text

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Induction of Vascular Permeability by the Sphingosine-1-Phosphate Receptor–2 (S1P2R) and its Downstream Effectors ROCK and PTEN

Teresa Sánchez, Athanasia Skoura, Ming Tao Wu et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2007 · 328 citations · Full text

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Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma

Jagan Muppidi, Roland Schmitz, Jesse A. Green et al. · Nature · 2014 · 291 citations · Full text

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The G Protein–Coupled Receptor S1P2 Regulates Rho/Rho Kinase Pathway to Inhibit Tumor Cell Migration

Denise Lepley, Jihye Paik, Timothy Hla et al. · Cancer Research · 2005 · 188 citations

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Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist

Makoto Osada, Yutaka Yatomi, Tsukasa Ohmori et al. · Biochemical and Biophysical Research Communications · 2002 · 188 citations

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