Hierarchical clustering of immunohistochemical analysis of the activated ErbB/PI3K/Akt/NF-κB signalling pathway and prognostic significance in prostate cancer

Abstract

These results validate the previous in vitro data on ErbB involvement in NF-kappaB activation and shows evidence for a significant role of ErbB/PI3K/Akt/NF-kappaB signalling in the progression of prostate cancer.