Concepedia

Inhibition of p38 MAPK improves intestinal disturbances and oxidative stress induced in a rabbit endotoxemia model

Sergio Gonzálo, Laura Grasa, María Pilar Arruebo, Miguel Ángel Plaza, María Divina Murillo

Neurogastroenterology & Motility · 2009 · 23 citations · 40 references

DOI

Abstract

Lipopolysaccharide decreases the duodenal contractility in rabbits and increases the production of free radicals. p38 MAPK is a mediator of these effects.

References

40

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Hermann Esterbauer, Kevin H. Cheeseman · Methods in enzymology on CD-ROM/Methods in enzymology · 1990 · 3.3K citations

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[37] Carbonyl assays for determination of oxidatively modified proteins

Rodney L. Levine, Joy Williams, Earl P. Stadtman et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1994 · 2.7K citations

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

Ana Cuenda, J.B. Rouse, Yair N. Doza et al. · FEBS Letters · 1995 · 2.1K citations

Pyridinyl Imidazole Inhibitors of p38 Mitogen-activated Protein Kinase Bind in the ATP Site

Peter R. Young, Megan M. McLaughlin, Sanjay Kumar et al. · Journal of Biological Chemistry · 1997 · 573 citations · Full text

Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease

Lisa Lih-Brody, Saul R. Powell, Kevin P. Collier et al. · Digestive Diseases and Sciences · 1996 · 498 citations

, , +7