DURATION OF LAST DEPRESSIVE EPISODE MAY INFLUENCE SERUM BDNF LEVELS IN REMITTED PATIENTS WITH MAJOR DEPRESSION

Abstract

Serum BDNF levels in remitted patients with MDD did not recover to the level of healthy controls, and lower serum BDNF levels were influenced by a longer duration of last depressive episode. It is possible that persistent hippocampal reduction in remitted depression may be caused by lower BDNF levels associated with a longer duration of the last depressive episode.