Tumor-infiltrating lymphocytes from human ovarian cancer patients recognize autologous tumor in an MHC class II-restricted fashion. - Concepedia

Concepedia

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Tumor-infiltrating lymphocytes from human ovarian cancer patients recognize autologous tumor in an MHC class II-restricted fashion.

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References

2006

Year

Roya Dadmarz, A Ordoubadi, Arnold Mixon, C O Thompson, Kathleen C. Barracchini, Yasmine M. Hijazi, Michael A. Steller, Steven A. Rosenberg, Douglas J. Schwartzentruber

Abstract

We believe these data are the first to suggest that tumor reactive CD4+ lymphocytes exist in some ovarian cancer patients. This finding may be useful in the development of novel immunotherapies for these patients.