‘Nucleo-nanocages’: designed ternary oligodeoxyribonucleotides spontaneously form nanosized DNA cagesElectronic supplementary information (ESI) available: a time course of absorbance increase of the ligated nucleo-nanocages 1–3, due to the enzymatic action of DNase I. See http://www.rsc.org/suppdata/cc/b2/b210139d/

Abstract

DNA three-way junctions formed from three 30-mer oligonucleotides that contain single-chained self-complementary sticky ends spontaneously self-assemble into 'nucleo-nanocages': the exo- and endo-nuclease digestion experiments indicate that defects such as the single and double strand end structures are absent on the spherical nano-assemblies, providing clear evidence for the closed nanocage structure.