Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV‐PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1‐¹³C]pyruvate

Abstract

These hyperpolarized (13)C MRS findings indicate that tumor metabolic changes affects kP. The measured kp did not relate to treatment response to the same extent as did tumor growth, histological evaluation, and in vitro determination of LDH activity.