Journal of Bacteriology · 1977 · 23 citations · 15 references
Life SciencesMicrobiologyMolecular BiologyDna RepairNucleic Acid BiochemistryRadiobiologyDna DamageDna Double-strand Break RepairDna Strand BreaksDouble-strand Break RepairDna Double-strand BreaksDna Repair InductionDna Repair MechanismsDna Strand Break RepairDouble-strand Dna BreaksEscherichia ColiRadiation-resistant MicrobiologyRepair Of Ionizing Radiation-induced Breaks
Freeze-drying of Escherichia coli cells caused strand breaks of deoxyribonucleic acid (DNA) in both radiation-sensitive and -resistant strains. However, in the radiation-resistant strain E. coli B/r the damaged DNA was repaired after rehydration, whereas in the radiation-sensitive strain E. coli Bs-1 the damaged DNA was not repaired and the DNA was degraded. Repeated freeze-drying did not break the damaged DNA into smaller pieces.
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