Neurological Complications of Lymphomas and Leukemias

Abstract

In a retrospective study, the authors have reviewed the hospital records of 5,778 patients with Hodgkin's disease, lymphosarcoma, multiple myeloma, and leukemia. A total of 795 neurobogic complications occurring in 745 patients were discovered which represented a patient incidence of approximately 13%. The complications which were encountered included spinal cord compression, infiltration of intracranial structures, compression and infiltration of peripheral and cranial nerves, intracranial hemorrhage, infiltration or invasion of the pituitary by tumor cells, and central nervous system infections occurring in association with the various malignancies.