Challenging the Two Concepts in Determining the Appropriate Pre-Discharge N-Terminal Pro-Brain Natriuretic Peptide Treatment Target in Acute Decompensated Heart Failure Patients: Absolute or Relative Discharge Levels?

Abstract

In an ADHF population, pre-discharge absolute or relative NT-proBNP targets may both be useful as they have similar effects on PARF. However, depending on admission NT-proBNP, absolute targets show varying PARFs, while PARFs for relative targets were similar. A relative target is predicted to reduce mortality consistently across the whole spectrum of ADHF patients, while this is not the case using a single absolute target.