Mapping the 3D Connectivity of the Rat Inner Retinal Vascular Network Using OCT Angiography

Abstract

Our graphing and modeling data suggest that vascular architecture enables both local and lamina-specific control of blood flow in the inner retina. The imaging, graph analysis, and modeling approach presented here will help provide a detailed characterization of vascular changes in a variety of retinal diseases, both in experimental preclinical models and human subjects.