Hepatic and splenic stiffness augmentation assessed with MR elastography in an in vivo porcine portal hypertension model

Abstract

The observed stiffness-pressure relationship of the liver and spleen could provide a promising noninvasive method for assessing portal pressure. Using MRE to study the tissue mechanics associated with portal pressure may provide new insights into the natural history and pathophysiology of hepatic diseases and may have significant diagnostic value in the future.