In Vitro Susceptibility of Bacterial Keratitis Isolates to Fourth-Generation Fluoroquinolones

Abstract

Monotherapy with moxifloxacin or gatifloxacin can be an effective alternative to cefazolin-tobramycin combination as a first-line empirical therapy for bacterial keratitis. The addition of cefazolin to a fourth-generation fluoroquinolone is of limited value.