E- Cigarette acute effect on symptoms and airway inflammation: comparison of nicotine with a non-nicotine cigarette

Abstract

Materials and methods We studied 64 subjects (aged 22-65 years, 34 men) divided in 2 groups. Group A: 12 never smokers and 29 healthy smokers smoked for 10 min a single e-cigarette containing 11mg of nicotine and Group B: 14 never smokers and 9 healthy smokers smoked a single e-cigarette containing 0mg of nicotine. The same brand of e-cig was used in both groups with similar liquid ingredients but with two different nicotine concentrations. Vital signs, symptoms questionnaire, Oxygen Saturation (SpO2), heart rate(HR)] and indices of airway inflammation (exhaled NO, and airways temperature) were assessed pre and post smoking.