Anti-Inflammatory Activities of a New Series of Selective Phosphodiesterase 4 Inhibitors Derived from 9-Benzyladenine

Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta

Claire Lugnier, Philippe Schoeffter, Alain Le Bec et al. · Biochemical Pharmacology · 1986 · 296 citations

Selective Inhibition, Biochemistry, Medicine +6

Stereospecific binding of the antidepressant rolipram to brain protein structures

Herbert H. Schneider, Ralph Schmiechen, Marina Brezinski et al. · European Journal of Pharmacology · 1986 · 236 citations

Psychiatry, Neuroanatomy, Medicine +7

Neutrophil-mediated Pulmonary Vascular Injury: Synergistic Effect of Trace Amounts of Lipopolysaccharide and Neutrophil Stimuli on Vascular Permeability and Neutrophil Sequestration in the Lung

G. Scott Worthen, Christopher Haslett, A. J. Rees et al. · American Review of Respiratory Disease · 1987 · 227 citations

Acute Lung Injury, Lung Inflammation, Immunology +19

The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells

J. Semmler, H. Wachtell, Stefan Endres · International Journal of Immunopharmacology · 1993 · 221 citations

Inflammation, Thrombopoiesis, Anti-inflammatory +8

The Association of Circulating Endotoxin with the Development of the Adult Respiratory Distress Syndrome

Polly E. Parsons, G. Scott Worthen, Ernest E. Moore et al. · American Review of Respiratory Disease · 1989 · 180 citations