Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

Nucleic Acid Chemistry, Engineering, Natural Sciences +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

Engineering, Natural Sciences, Rna Isolation +7

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Inês Barroso, Mark Gurnell, Vivion Crowley et al. · Nature · 1999 · 1.4K citations · Full text

Insulin Resistance, Metabolic Syndrome, Genetic Determinant +13

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

Samir S. Deeb, Lluís Fajas, Masami Nemoto et al. · Nature Genetics · 1998 · 1.3K citations · Full text

Insulin Resistance, Metabolic Syndrome, Molecular Pharmacology +14

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

Charles Barlowe · Cell · 1994 · 1.3K citations

Protein Secretion, Sec Proteins, Secretory Pathways +9