Decarboxylative Julia–Kocienski <i>gem</i>‐Difluoro‐Olefination of 2‐Pyridinyl Sulfonyldifluoroacetate

Abstract

Abstract The decarboxylation of potassium 2‐pyridinyl sulfonyldifluoroacetate and its subsequent reaction with aldehydes was found to be an efficient approach for the Julia–Kocienski reaction under mild conditions to give gem ‐difluoro olefins in moderate to excellent yields. Owing to its high stability in the pure state and its easy decarboxylation in polar solvents, potassium 2‐pyridinyl sulfonyldifluoroacetate is expected to be an efficient gem ‐difluoro‐olefination reagent.