Concepedia

A prospective, multicenter study of cardiac-based seizure detection to activate vagus nerve stimulation

Paul Boon, Kristl Vonck, Kenou van Rijckevorsel, Riëm El Tahry, Christian E. Elger, Nandini Mullatti, Andreas Schulze‐Bonhage, Louis Wagner, Beate Diehl, Hajo M. Hamer,

Seizure · 2015 · 196 citations · 18 references

DOIFull text

Open access

Abstract

The investigated CBSDA has a high sensitivity and an acceptable specificity for triggering VNS. Despite the moderate effects on seizure frequency, combined open- and closed-loop VNS may provide valuable improvements in seizure severity and QOL in refractory epilepsy patients.

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