Early and selective disappearance of telethonin protein from the sarcomere in neurogenic atrophy

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

Dieter O. Fürst, Mary Osborn, Rüdiger Nave et al. · The Journal of Cell Biology · 1988 · 622 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Structural basis for activation of the titin kinase domain during myofibrillogenesis

Olga Mayans, Peter F. M. van der Ven, Matthias Wilm et al. · Nature · 1998 · 361 citations

Life Sciences, Biochemistry, Molecular Biology +14

Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin

Eloísa S. Moreira, Tim Wiltshire, Georgine Faulkner et al. · Nature Genetics · 2000 · 334 citations

Medicine, Genetics, Molecular Genetics +13

Muscle-specific Calpain, p94, Responsible for Limb Girdle Muscular Dystrophy Type 2A, Associates with Connectin through IS2, a p94-specific Sequence

Hiroyuki Sorimachi, Kayoko Kinbara, Sumiko Kimura et al. · Journal of Biological Chemistry · 1995 · 326 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Molecular structure of the sarcomeric Z‐disk: two types of titin interactions lead to an asymmetrical sorting of α‐actinin

Paul Young · The EMBO Journal · 1998 · 250 citations

Life Sciences, Cell Biology, Molecular Biology +10