Cerebrovascular permeability studies in cerebral neolasms and vascular lesions: optimal dose-to-scan interval for pertechnetate brain scanning.

Abstract

Summary Brain scans were performed in a series of patients at various intervals after injection of 98mTc-pertechnetate. The optimal interval between injection and scanning seems to be at least 3 hr. Our data suggest that scanning at this time leads to the greatest accuracy in diagnosing the positive scans with the least number of false-positive and false-negative reports. A method of analyzing scintiscan data is presented. This is based on the derivation of ratios based on actual counting rates obtained from digitized computer-processed scintiscan matrices.