Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally?

Abstract

These findings illustrate a dichotomy in regional responses to TESI. Although scar size reduction was evident in all scar segments, scar size reduction and ventricular functional responses preferentially occurred at the sites of TESI versus non-TESI sites. Furthermore, improvement was greatest when segmental left ventricular dysfunction was severe.