The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65

The Anti-inflammatory Sesquiterpene Lactone Helenalin Inhibits the Transcription Factor NF-κB by Directly Targeting p65

Guido Lyß, Alexander Knorre, Thomas J. Schmidt et al. · Journal of Biological Chemistry · 1998 · 472 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Cysteine 38 in p65/NF-κB Plays a Crucial Role in DNA Binding Inhibition by Sesquiterpene Lactones

Alfonso García‐Piñeres, Vı́ctor Castro, Gerardo Mora et al. · Journal of Biological Chemistry · 2001 · 401 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB

Peter M. Bork, M. Lienhard Schmitz, Michaela Kuhnt et al. · FEBS Letters · 1997 · 328 citations · Full text

Life Sciences, Botany, Plant Sciences +12

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

Thomas Efferth, A. Benakis, Marta R. Romero et al. · Free Radical Biology and Medicine · 2004 · 269 citations

Medicine, Oncology, Pharmacology +14

Quantitative Structure−Activity Relationship of Sesquiterpene Lactones as Inhibitors of the Transcription Factor NF-κB

Bettina Siedle, Alfonso García‐Piñeres, Renato Murillo et al. · Journal of Medicinal Chemistry · 2004 · 243 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16