Successful “in‐flight” activation of natural killer cells during long‐distance shipping

Abstract

The need for novel cell therapies to be infused as fresh products may be a limitation for various cell types. However, we have shown that NK cells can be successfully shipped in the fresh state (allowing 48 hr from apheresis to product infusion) for use at clinical centers. Although IL-2 is critical for NK-cell activation, a 37 °C, 5% CO2 incubator is not.