Concepedia

Safeguarding gene drive experiments in the laboratory

Omar S. Akbari, Hugo J. Bellen, Ethan Bier, Simon L. Bullock, Austin Burt, George M. Church, Kevin R Cook, Peter Duchek, Owain R. Edwards, Kevin M. Esvelt,

Science · 2015 · 288 citations · 12 references

DOI

Concepts

Abstract

Multiple stringent confinement strategies should be used whenever possible

References

12

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in <i>Drosophila</i>

Fillip Port, Hui-Min Chen, Tzumin Lee et al. · Proceedings of the National Academy of Sciences · 2014 · 1.2K citations · Full text

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Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in <i>Drosophila</i>

Scott J. Gratz, Fiona P. Ukken, C. Dustin Rubinstein et al. · Genetics · 2014 · 1.1K citations · Full text

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Site-specific selfish genes as tools for the control and genetic engineering of natural populations

Austin Burt · Proceedings of the Royal Society B Biological Sciences · 2003 · 758 citations · Full text

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Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in <i>Drosophila</i>

Shu Kondo, Ryu Ueda · Genetics · 2013 · 641 citations · Full text

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The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations

Valentino M. Gantz, Ethan Bier · Science · 2015 · 636 citations · Full text

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