Adjuvant effects of diethylaminoethyl-dextran

William E. Houston, C. L. Crabbs, Robert Kremer, Jan Springer

Infection and Immunity · 1976 · 31 citations · 13 references

DOIFull text

Open access

Concepts

Abstract

Diethylaminoethyl-dextran exhibited a significant effect on the primary immune response of rhesus monkeys to formalin-inactivated Venezuelan equine encephalomyelitis virus vaccine (IVEE). Antibody formed to IVEE and adjuvant followed a classic immunoglobulin M-immunoglobulin G pattern; however, as compared with vaccine alone, use of this adjuvant with IVEE reduced the time required for onset of immunoglobulin G synthesis.

References

13