Chemical Communications · 2004 · 87 citations · 32 references
PharmacyChemistryAnalytical ChemistryChromatographic AnalysisSeparation ScienceAnalytical ChromatographyChromatographic Impurity SeparationChromatographic PurificationChromatographyInstrumental AnalysisStationary Phase ChemistryChromatographic Purification Of ImpuritiesChromatographic Residue DeterminationColumn ChromatographyHigh-performance Liquid Chromatography Stationary PhasesPurificationSilica Stationary PhasesSolvent OptimizationTin Chemistry
Through the simple expedient of using a mixture of KF and silica as the stationary phase in column chromatography, levels of organotin impurities from tributyltin hydride mediated reductions have been reduced from stoichiometric levels to approximately 30 ppm.
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